Revolutionizing Treatment for Type 1 Diabetes
Recreating the biological systems responsible for insulin production.
MissionRecreating the biological systems responsible for insulin production.
MissionWe want eliminate the risks and inconvenience that type 1 diebetic patients face, to enhance their quality of life.
Currently, 436 million people have type 1 diabetes all around the world. This chronic conditon comes with a lot of challenges, such as inaccurage dosages would could lead to hyperglycemia or hypoglycemia. Missing just a single dose of insulin could put your life at risk.
We use an artifical pancreas that's implanted into the patient's body to detect and secrete insulin when needed. Nanosensors are also implanted into the body's bloodstream to aid in monitor glucose levels, 24/7. Lastly, in-vivo networking allows the nanosensors to communicate the glucose reports to the patient's smart device.
By getting this one-time treatment, patients are able to save 76% of the cost they would've had to pay in total at the age of 20 (assuming the average age is 13). Besides the reducation in the costs, these patients are able to live a life of comfort, convenience, and well-being without the lifelong insulin therapy.
We take the patient's own stem cells, and turn them into beta cells- cells responsible for insulin production. We then use those same beta cells, and turn them into a bioink in order to 3D print an artificial pancreas. The pancreas will be fully vascularized, preventing cell death.
We also emmbed nanosensors that are specifically designed to detect blood glucose levels, onto a stent. The stent is then placed in the hepatic portal vein, where it is able to monitor the patient's glucose levels at all times.
By using in-vivo networking, we're able to communicate with the smallest devices, implanted deep into the body. This allows nanosensors to be wireessly power up (no need for batteries anymore, which was a huge barrier previosuly), the nanosensors. As well, the nanosensors are able to communicate with the patient's smart device so they have reports on their glucose levels, in real-time values.
Use our user-friendly app, where you'll get real-time reports on your glucose levels through the information collected through the nano-sensors implanted in your bloodstream.
You'll be able to get a detailed analysis on your glucose levels daily, weekly, and monthly. As well as an analysis on your daytime and nighttime highs. The app is also able to identify information on the status of the nanosensors, such as the average number of calibration. As a Metanoia customer, you're able to know exactly what's happening in your body, at all times.
Metatonia ensures this doesn’t happen again, by wrapping the produced beta and alpha cells with Alginate which is one of the most frequently used biomaterials in the field of cell microencapsulation, has been demonstrated to be probably the best polymer for this purpose due to its biocompatibility, easy manipulation, gel forming capacity, non-immunogenicity and in vivo performance. It is a kind of polysaccharide refined from brown seaweeds. We would use this biomaterial as a membrane for our artificial pancreas to prevent the patient’s immune system from attacking it.
If for some reason the beta cells stop functioning, despite the cell encapsulation, Metatonia takes care of this by taking advantage of the patient’s stem cells once again. Stem cells are useful as we have a large amount of them in our body. Adults have on average 50,000 to 200,000 stem cells in their body, which we can use to our advantage. We can easily take out the required amount of the patient’s stem cells by removing some blood temporarily, isolating and collecting the stem cells, then inserting the blood back into the body.
